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id="whlhjwdz9w" class="ny_title"> <span id="whlhjwdz9w" class="left"> <strong>技术文章 </strong>/ article </span> <span id="whlhjwdz9w" class="right"><img src="/skins/339218/images/home.png">您的位置：<a href="/">网站首页</a> > <a href="/article.html">技术文章</a> > 不同工作方式小动物呼吸机使用小知识</span> </div> <div id="whlhjwdz9w" class="right_content"> <div id="whlhjwdz9w" class="art-cont"> <h1 class="art-title">不同工作方式小动物呼吸机使用小知识</h1> <div id="whlhjwdz9w" class="art-info"> 发布时间： 2018-12-10　　点击次数： 2121次 </div> <div id="whlhjwdz9w" class="art-body"> 　　不同工作方式小动物呼吸机使用小知识<br />　　机械通气是在患者自然通气或者氧合功能出现障碍时运用器械，使患者恢复有效通气并改善氧合的方法。其中常用的器械成为“呼吸机”。<br />　　机械通气这种手段为临床医学研究中*的生命支持手段，为进行动物实验和动物疾病治疗提供了时间，极大的提高了一些长时间性实验或者开胸等呼吸衰竭实验的成功率。<br />　　关于呼吸机历史还蛮悠久的，这里我们简单回顾下：<br />　　早在罗马帝国时代，呼吸机就有一个雏形。1792年，当时在慈善协会(Royal Humanne Society)的支持下，在人身上实施气管切开、插管及风箱式正压通气技术，用于溺水患者的复苏，在当时欧洲被广泛接受。后面因为会产生致命性的气胸被终止。到了20世纪，由Driker-Shaw在1928年研制成的“铁肺”（iron lung），使当时脊髓灰质炎的死亡率大大降低。开始了一种负压通气的模式。<br />　　而现今我们在市面上看到不同工作方式的的小动物呼吸机。那么他们之间又是怎样区分的呢?<br />　　1、依据不同的吸气控制方式，可以将呼吸机分为压力控制型呼吸机和容量控制型呼吸机，在临床呼吸机领域，压力控制更主流一些。在但动物实验领域，相当多的用户习惯设置潮气量进行容积控制。<br />　　2、依据呼吸机的结构原理，可分为活塞式呼吸机和电磁阀式呼吸机。一般活塞式呼吸机使用容积控制，而电磁阀式呼吸机即可以进行容控制，也可以进行压力控制。<br />　　3、依据调控方式不同，可分为电动电控型和气动电控型呼吸机。<br />　　因为具有不同的呼吸机，其实他们给动物的通气方式也是不同的，根据通气方式不同，我们可以将通气方式分为：<br />　　控制模式（CV）：呼吸机*替代实验动物的呼吸，其呼吸频率，潮气量均由呼吸机控制，属于*的呼吸支持。适用于自主呼吸消失或很微弱的情况，比较典型的应用，就是动物的开胸手术实验。根据控制参数的不同，控制通气又可以分为容量控制通气(VCV）和压力控制通气(PCV)。容量控制通气(VCV）是呼吸机按预置的潮气量、呼吸频率、呼吸比等参数完成通气。压力控制通气(PCV)则是呼吸机按照预置的频率、呼吸比、吸气压力工作。<br />　　辅助通气（AV）: 呼吸机的送气是通过呼吸机检测实验动物的气道压的降低来触发。辅助通气是一种与临床应用类似的呼吸方式，动物的辅助通气一般可以通过设置压力触发、人工触发或定时触发等方式启动。对于小动物呼吸机而言，辅助通气(AV）是一种较的呼吸模式，仅少量小动物呼吸机具体此功能。<br />　　叹气模式(sigh): 是一种在常规呼吸通气条件下，隔一段时间进行一次深呼吸的通气方式。通常实验动物在长期使用控制通气，尤其是容量控制通气条件下，某些边缘肺泡会膨胀不全，肺部功能会逐步减弱，加入定时或手工叹气，可防止肺部萎陷不张，改善气体交换性能。 </div> <div id="whlhjwdz9w" class="art-next"> <dl class="shangxia"> <dd>上一篇：<a href="/Article-1693482.html">竹园中为何可以应用病虫检验检疫箱？</a> </dd> <dd>下一篇：<a href="/Article-1720983.html">标本工具箱对病虫害研究的积极意义</a> </dd> </dl> </div> </div> </div> </div> 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